Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access
Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc
Journal website https://www.cardiologyres.org

Original Article

Volume 3, Number 2, April 2012, pages 67-72


Clopidogrel Therapy Discontinuation Following Drug Eluting Stent Implantation in Real World Practice in Israel

Figures

Figure 1.
Figure 1. Antiplatelet therapy during the follow up, n = 269.
Figure 2.
Figure 2. Distribution of reasons for stopping clopidogret therapy during the follow up, n = 269.

Tables

Table 1. Baseline Characteristics of the Study Population (n = 314)
 
VariableNumber/Mean ± SDPercentage
Data are expressed as mean ± SD or as number (percentage). LDL: low density lipoprotein; STEMI: ST elevation myocardial infarction; LVEF: left ventricular ejection fraction on echocardiography.
Male sex26082.8
Age, years60 ± 10.5
Jew21668.8
High school education6721.3
Receives National Insurance Benefits3210.2
Hypertension20565.3
Diabetes Mellitus13843.9
Current smoker10232.5
Body mass index29.5 ± 5.5
LDL level mg/dL109.3 ± 35.8
Previous myocardial infarction10934.7
Previous thromboembolic event175
Acute coronary syndrome,18859.8
STEMI4012.7
LVEF < 40%3711.7
Multivessel disease19461.8
Refferal to Cardiologist16352
Instruction by doctor at discharge22471

 

Table 2. Multiple Logistic Regression Analysis for Predictors of Early Discontinuing Clopidogrel Therapy Within 3 Months
 
VariableUnivariable analysisMultivariable analysis
OR (95% CI)POR (95% CI)P
OR: odds ratio; CI: confidence interval.
Non Jew13.6 (3.6 - 51.1)0.00119.2 (2.4 - 142)0.005
No high education3.7 (0.8 - 16.1)0.052.2 (0.2 - 24.4)0.5
National insurance benefits (unemployed)0.0031.3 (0.1 - 13.4)0.8
Not referred to cardiologist2.2 (1 - 5.3)0.0874.7 (1 - 23.1)0.05
No medication instruction by doctor at discharge7.5 (3.3 - 17.1)< 0.000110.8 (2.7 - 42.9)0.001