Cardiol Res

Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access

Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc

Journal website https://www.cardiologyres.org

Original Article

Volume 13, Number 3, June 2022, pages 128-134

Comparison of Tricuspid Regurgitation Severity Between Cardiac Resynchronization Therapy Versus Right Ventricular Pacing in Patients With Chronic Obstructive Pulmonary Disease

Figure 1. Cardiac resynchronization therapy (CRT) group tricuspid regurgitation (TR) severity pre- vs. post-device implantation.

Figure 2. Single-chamber pacemaker (PM) or implantable cardioverter-defibrillator (ICD) group tricuspid regurgitation (TR) severity pre-device vs. post-device implantation.

Figure 3. Dual-chamber pacemaker (PM) or implantable cardioverter-defibrillator (ICD) group tricuspid regurgitation (TR) severity pre-device vs. post-device implantation.

Figure 4. Comparison of worsening tricuspid regurgitation (TR) between the three groups: 1) cardiac resynchronization therapy (CRT); 2) single-chamber pacemaker (PM) or implantable cardioverter-defibrillator (ICD); and 3) dual-chamber PM or ICD.

**Table 1.** Baseline Characteristics of Patients
Characteristics	CRT (n = 37)	Single-chamber PPM/ICD (n = 27)	Dual-chamber PPM/ICD (n=90)	P value
Variables are expressed as no (%) or mean ± standard deviation. P < 0.05 indicates difference between the groups is statistically significant. CRT: cardiac resynchronization therapy; PPM: permanent pacemaker; ICD: implantable cardioverter-defibrillator; CRT-D: cardiac resynchronization therapy defibrillator; CRT-P: cardiac resynchronization therapy pacemaker; ICD-S: implantable cardioverter-defibrillator single-chamber; PPM-S: permanent pacemaker single-chamber; PPM-D: permanent pacemaker dual-chamber; ICD + PPM-D: implantable cardioverter-defibrillator with permanent pacemaker dual-chamber; RVSP: right ventricular systolic pressure.
Age (years)	70.22 ± 9.37	70.07 ± 10.06	72.79 ± 11.15	0.32
Male sex	23 (62.16%)	16 (59.26%)	46 (51.11%)	0.46
Device subtypes
CRT-D	19 (51.35%)
CRT-P	18 (49.65%)
ICD-S		8 (29.63%)
PPM-S		19 (70.37%)
PPM-D			80 (88.89%)
ICD + PPM-D			10 (11.11%)
Ejection fraction (%)
Pre-device implantation	33.53±10.86%	45.56±13.68%	51.29 ± 11.20	< 0.0001
Post-device Implantation	46.53±13.14%	49.26±11.82%	50.69±13.34%	0.41
RVSP (mm Hg)
Pre-device implantation	31.82 ± 8.42	34.65 ± 7.22	35.73 ± 14	0.42
Post-device implantation	40.54 ± 16.07	46.41 ± 16.31	39.07 ± 13.42	0.11

Table 1. Baseline Characteristics of Patients

Characteristics

CRT (n = 37)

Single-chamber PPM/ICD (n = 27)

Dual-chamber PPM/ICD (n=90)

P value

Variables are expressed as no (%) or mean ± standard deviation. P < 0.05 indicates difference between the groups is statistically significant. CRT: cardiac resynchronization therapy; PPM: permanent pacemaker; ICD: implantable cardioverter-defibrillator; CRT-D: cardiac resynchronization therapy defibrillator; CRT-P: cardiac resynchronization therapy pacemaker; ICD-S: implantable cardioverter-defibrillator single-chamber; PPM-S: permanent pacemaker single-chamber; PPM-D: permanent pacemaker dual-chamber; ICD + PPM-D: implantable cardioverter-defibrillator with permanent pacemaker dual-chamber; RVSP: right ventricular systolic pressure.

Age (years)

70.22 ± 9.37

70.07 ± 10.06

72.79 ± 11.15

0.32

Male sex

23 (62.16%)

16 (59.26%)

46 (51.11%)

0.46

Device subtypes

CRT-D

19 (51.35%)

CRT-P

18 (49.65%)

ICD-S

8 (29.63%)

PPM-S

19 (70.37%)

PPM-D

80 (88.89%)

ICD + PPM-D

10 (11.11%)

Ejection fraction (%)

Pre-device implantation

33.53±10.86%

45.56±13.68%

51.29 ± 11.20

< 0.0001

Post-device Implantation

46.53±13.14%

49.26±11.82%

50.69±13.34%

0.41

RVSP (mm Hg)

Pre-device implantation

31.82 ± 8.42

34.65 ± 7.22

35.73 ± 14

0.42

Post-device implantation

40.54 ± 16.07

46.41 ± 16.31

39.07 ± 13.42

0.11

**Table 2.** Baseline Tricuspid Regurgitation
Degree of TR	CRT (n = 37)	Single-chamber device (n = 27)	Dual-chamber device (n = 90)
TR: tricuspid regurgitation; CRT: cardiac resynchronization therapy.
Mild	28	23	81
Moderate	8	4	9
Severe	1	0	0

Table 2. Baseline Tricuspid Regurgitation

Degree of TR

CRT (n = 37)

Single-chamber device (n = 27)

Dual-chamber device (n = 90)

TR: tricuspid regurgitation; CRT: cardiac resynchronization therapy.

Mild

Moderate

Severe