Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access
Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc
Journal website https://www.cardiologyres.org

Original Article

Volume 12, Number 6, December 2021, pages 329-334

Hemodynamic and Respiratory Effects of Regadenoson During Radiologic Imaging in Infants and Children

Figure

Figure 1.
Figure 1. Heart rate and blood pressure changes following the administration of regadenoson. The individual patients are listed in black and the average in red. The administration of regadenoson occurred at time 0. Individual patient data are listed in black with the average values in red. sBP: systolic blood pressure; dBP: diastolic blood pressure; MAP: mean arterial pressure; HR: heart rate.

Tables

Table 1. Demographic Data of the Study Cohort
 
Gender is listed as the number (percentage) while the other data are listed as the median and range.
Gender, male8 (100%)
Age (years)4.3 (2, 6.2)
Weight (kg)19.9 (10, 30.5)
Body mass index (kg/m2)15.6 (12.8, 23.3)

 

Table 2. Anesthetic Data of the Study Cohort
 
VariableNumber (%)Mean ± SD
SD: standard deviation.
Total anesthesia time (min)98.6 ± 7.3
Premedication3 (37.5%)
  Oral midazolam (mg)7 ± 1.7
Inhaled anesthetic agent
  Sevoflurane7 (87.5%)
  Isoflurane1 (12.5%)
Intravenous anesthetic medications
  Propofol (mg)4 (50%)25 ± 5.8
  Ondansetron (mg)7 (87.5%)2.5 ± 0.8
  Dexamethasone (mg)4 (50%)3.3 ± 1.5
Airway, endotracheal tube8 (100%)
Regadenoson dose (µg)8 (100%)148 ± 49
Aminophylline dose (mg)8 (100%)4.7 ± 1.6
Bradycardia treatment0 (0%)
Hypotension treatment, phenylephrine (µg)4 (50%)
  Dose 14 (50%)20 ± 14
  Dose 23 (37.5%)13 ± 6
  Dose 33 (37.5%)15 ± 5

 

Table 3. Hemodynamic Changes After Regadenoson
 
VariableNumber (%)
Mean arterial pressure
  Number of patients with a decrease ≥ 10 mm Hg5 (62.5%)
  Number of patients with a decrease ≥ 20 mm Hg2 (25%)
  Number of patients with a decrease ≥ 30 mm Hg0 (0%)
  Greatest decrease in mean arterial pressure21 mm Hg
Systolic blood pressure
  Number of patients with a decrease ≥ 10mm Hg8 (100%)
  Number of patients with a decrease ≥ 20 mm Hg6 (75%)
  Number of patients with a decrease ≥ 30 mm Hg2 (25%)
  Greatest decrease in systolic blood pressure37 mm Hg
Diastolic blood pressure
  Number of patients with a decrease ≥ 10mm Hg5 (62.5%)
  Number of patients with a decrease ≥ 20 mm Hg1 (12.5%)
  Greatest decrease in diastolic blood pressure22 mm Hg
Heart rate
  Number of patients with increase ≥ 20 beats/min6 (75%)
  Number of patients with increase ≥ 30 beats/min2 (25%)
  Number of patients with increase ≥ 40 beats/min0 (0%)
  Greatest increase in heart rate36 beats/min