Cardiol Res

Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access

Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc

Journal website https://www.cardiologyres.org

Original Article

Volume 7, Number 1, February 2016, pages 1-8

Significant Increase in C-Reactive Protein and Serum Amyloid A in the Early Hours of Paroxysmal Atrial Fibrillation

Figures

Figure 1. Changes in plasma concentration of hs-CRP (mg/L) in patients with PAF. Baseline values: hs-CRP values upon patients’ hospitalization; 24th hour: values 24 h after sinus rhythm restoration; 28th day: values 28 days after sinus rhythm restoration; *P < 0.05; **P < 0.001; ns: statistically insignificant difference.

Figure 2. Changes in plasma concentration of SAA (ng/mL) in patients with PAF. Baseline values: hs-CRP values upon patients’ hospitalization; 24th hour: values 24 h after sinus rhythm restoration; 28th day: values 28 days after sinus rhythm restoration; **P < 0.001; ns: statistically insignificant difference.

Figure 3. Plasma levels of fibrinogen (g/L) in patients with PAF. Baseline values: hs-CRP values upon patients’ hospitalization; 24th hour: values 24 h after sinus rhythm restoration; 28th day: values 28 days after sinus rhythm restoration; ns: statistically insignificant difference.

Figure 4. Probability distribution of hs-CRP estimated using logistic model.

Figure 5. Probability distribution of SAA estimated using logistic model.

Tables

**Table 1.** Demographic Characteristics of Participants
	Patients with PAF	Control group	P values
Number of participants in the group	51	52	0.89
Mean age (years)	59.84 ± 1.60	59.50 ± 1.46	0.87
Men/women	26/25	26/26	1/0.93

**Table 2.** Clinical Characteristics of Patients and Control Subjects
	Patients with PAF	Control group	P values
Accompanying diseases
Hypertension	37 (72.54%)	34 (65.38%)	0.44
Diabetes mellitus type 2	3 (5.88%)	2 (3.84%)	0.62
Chronic ulcer disease	2 (3.92%)	0	0.15
Status after hysterectomy	2 (3.92%)	1 (1.92%)	0.54
Benign prostatic hypertrophy	1 (1.96%)	0	0.32
Dyslipidemia	4 (7.84%)	3 (5.77%)	0.69
Medicaments for hypertension and dyslipidemia
Beta blockers	19 (37.25%)	17 (32.69%)	0.62
ACE inhibitors	15 (29.41%)	14 (26.92%)	0.78
Sartans	11 (21.57%)	9 (17.31%)	0.58
Statins	4 (7.84%)	3 (5.77%)	0.69

**Table 3.** Deleterious Habits and BMI in Patients and Controls
	Patients with PAF	Control group	P values
Deleterious habits
Smoking	8 (15.69%)	7 (13.46%)	0.75
Alcohol intake	7 (13.72%)	6 (11.53%)	0.74
BMI (kg/m²)	23.85 ± 0.46	24.95 ± 0.45	0.09