| Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc |
| Journal website https://www.cardiologyres.org |
Original Article
Volume 6, Number 4-5, October 2015, pages 301-305
Prognostic Value of Left Ventricular End-Diastolic Pressure in Patients With Non-ST-Segment Elevation Myocardial Infarction
Tables
| LVEDP > 22 mm Hg (n = 109) | LVEDP ≤ 22 mm Hg (n = 258) | P value | |
|---|---|---|---|
| Data are expressed as a number (percent) or median (interquartile range). LVEDP: left ventricular end-diastolic pressure; PCI: percutaneous coronary intervention; CABG: coronary artery bypass grafting; TIMI: thrombolysis in myocardial infarction; eGFR: estimated glomerular filtration rate. *Chronic kidney disease was defined as eGFR < 60 mL/min/1.73 m2. | |||
| Demographics | |||
| Age (years) | 64 (54 - 74) | 66 (57 - 75) | 0.35 |
| Male | 68 (62) | 162 (63) | 0.94 |
| Body mass index (kg/m2) | 29.5 (25.6 - 33.1) | 26.5 (23.3 - 29.7) | < 0.001 |
| Hypertension | 87 (80) | 178 (69) | 0.03 |
| Diabetes mellitus | 55 (50) | 85 (33) | 0.001 |
| Hyperlipidemia | 64 (59) | 138 (53) | 0.35 |
| Chronic kidney disease* | 45 (41) | 68 (26) | 0.005 |
| Family history of coronary artery disease | 28 (26) | 51 (20) | 0.21 |
| Current smoker | 19 (17) | 65 (25) | 0.11 |
| History of heart failure | 15 (14) | 19 (7) | 0.053 |
| Previous PCI | 37 (34) | 59 (23) | 0.027 |
| Previous CABG | 20 (18) | 17 (7) | < 0.001 |
| Previous myocardial infarction | 22 (20) | 32 (12) | 0.055 |
| TIMI risk score | 0.23 | ||
| Low risk (0 - 2) | 17 (16) | 57 (22) | |
| Intermediate risk (3 - 4) | 59 (54) | 140 (54) | |
| High risk (5 - 7) | 33 (30) | 61 (24) | |
| Hemodynamic and laboratory data | |||
| Systolic blood pressure (mm Hg) | 144 (127 - 160) | 144 (126 - 159) | 0.63 |
| Diastolic blood pressure (mm Hg) | 80 (71 - 91) | 81 (73 - 93) | 0.71 |
| Heart rate (beat/min) | 85 (72 - 97) | 80 (70 - 92) | 0.08 |
| Hemoglobin (g/L) | 12.8 (11.3 - 14.1) | 13.3 (12.2 - 14.5) | 0.01 |
| White blood cell count (109/L) | 8.7 (7.0 - 10.9) | 8.5 (6.7 - 10.7) | 0.76 |
| eGFR (mL/min/1.73 m2) | 65 (45 - 81) | 78 (58 - 93) | 0.001 |
| Peak troponin I (μg/L) | 1.64 (0.15 - 7.54) | 0.55 (0.10 - 5.39) | 0.049 |
| Killip class on admission II-IV | 22 (20) | 30 (12) | 0.032 |
| Left ventricular ejection fraction (%) | 52 (33 - 60) | 60 (50 - 65) | < 0.001 |
| LVEDP > 22 mm Hg (n = 109) | LVEDP ≤ 22 mm Hg (n = 258) | P value | |
|---|---|---|---|
| Data are expressed as a number (percent) or median (interquartile range). LVEDP: left ventricular end-diastolic pressure; LAD: left anterior descending; TIMI: thrombolysis in myocardial infarction; PCI: percutaneous coronary intervention; CABG: coronary artery bypass grafting. | |||
| Angiographic findings | |||
| Interval to angiography from hospital admission (days) | 0.95 (0.57 - 1.77) | 1.21 (0.67 - 2.20) | 0.017 |
| LAD coronary artery culprit lesion | 28 (26) | 60 (23) | 0.62 |
| Multi-vessel disease | 59 (54) | 138 (53) | 0.91 |
| Collateral flow to infarcted related artery | 37 (34) | 65 (25) | 0.087 |
| Number of diseased vessels | |||
| 0 | 22 (20) | 57 (22) | 0.68 |
| 1 | 28 (26) | 63 (24) | 0.8 |
| 2 | 31 (28) | 72 (28) | 0.92 |
| 3 | 28 (26) | 66 (26) | 0.98 |
| Pre-procedural TIMI flow grade | 0.66 | ||
| 0/1 | 29 (27) | 63 (24) | |
| 2/3 | 80 (73) | 195 (76) | |
| In-hospital PCI | 49 (45) | 136 (53) | 0.17 |
| In-hospital CABG | 8 (7) | 28 (11) | 0.3 |
| In-hospital outcomes | |||
| All-cause mortality | 4 (4) | 1 (0.4) | 0.029 |
| Heart failure | 24 (22) | 34 (13) | 0.034 |